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Effectiveness of Naturally Acquired and Vaccine-Induced Immune Responses to SARS-CoV-2 Mu Variant
Emerging Infectious Diseases ( IF 11.8 ) Pub Date : 2022-07-13 , DOI: 10.3201/eid2808.220584
Edmilson F. de Oliveira-Filho , Bladimiro Rincon-Orozco , Natalia Jones-Cifuentes , Brigitte Peña-López , Barbara Mühlemann , Christian Drosten , Andres Moreira-Soto , Jan Felix Drexler

SARS-CoV-2 Mu variant emerged in Colombia in 2021 and spread globally. In 49 serum samples from vaccinees and COVID-19 survivors in Colombia, neutralization was significantly lower (p<0.0001) for Mu than a parental strain and variants of concern. Only the Omicron variant of concern demonstrated higher immune evasion.



中文翻译:

自然获得和疫苗诱导的对 SARS-CoV-2 Mu 变体的免疫反应的有效性

SARS-CoV-2 Mu 变体于 2021 年在哥伦比亚出现并在全球传播。在来自哥伦比亚疫苗接种者和 COVID-19 幸存者的 49 份血清样本中,Mu 的中和作用显着低于亲本菌株和相关变异株(p<0.0001)。只有关注的 Omicron 变体表现出更高的免疫逃避。

更新日期:2022-07-13
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