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Time to recovery and its predictors among critically ill patients on mechanical ventilation from intensive care unit in Ethiopia: a retrospective follow up study
BMC Emergency Medicine ( IF 2.5 ) Pub Date : 2022-07-12 , DOI: 10.1186/s12873-022-00689-3
Lehulu Tilahun 1 , Asressie Molla 2 , Fanos Yeshanew Ayele 3 , Aytenew Nega 4 , Kirubel Dagnaw 5
Affiliation  

For critically ill patients, mechanical ventilation is considered a pillar of respiratory life support. The mortality of victims in intensive care units is high in resource-constrained Sub-Saharan African countries. The recovery and prognosis of mechanically ventilated victims are unknown, according to evidence. The goal of the study was to see how long critically ill patients on mechanical ventilation survived. A retrospective follow-up study was conducted. A total of 376 study medical charts were reviewed. Data was collected through reviewing medical charts. Data was entered into Epi-data manager version 4.6.0.4 and analyzed through Stata version 16. Descriptive analysis was performed. Kaplan- Meier survival estimates and log rank tests were performed. Cox proportional hazard model was undertaken. Median recovery time was 15 days (IQR: 6–30) with a total recovery rate of 4.49 per 100 person-days. In cox proportional hazard regression, diagnosis category {AHR: 1.690, 95% CI: (1.150- 2.485)}, oxygen saturation {AHR: 1.600, 95% CI: (1.157- 2.211)}, presence of comorbidities {AHR: 1.774, 95% CI: (1.250–2.519)}, Glasgow coma scale {AHR: 2.451, 95% CI: (1.483- 4.051)}, and use of tracheostomy {AHR: 0.276, 95% CI: (0.180–0.422)} were statistically significant predictors. Based on the outcomes of this study, discussions with suggested possible reasons and its implications were provided. Duration and recovery rate of patients on mechanical ventilation is less than expected of world health organization standard. Diagnosis category, oxygen saturation, comorbidities, Glasgow coma scale and use of tracheostomy were statistically significant predictors. Mechanical ventilation durations should be adjusted for chronic comorbidities, trauma, and use of tracheostomy.

中文翻译:

埃塞俄比亚重症监护室机械通气危重患者的康复时间及其预测因素:一项回顾性随访研究

对于重症患者,机械通气被认为是呼吸生命支持的支柱。在资源有限的撒哈拉以南非洲国家,重症监护病房的受害者死亡率很高。根据证据,机械通气患者的康复和预后尚不清楚。该研究的目的是了解机械通气的重症患者存活多长时间。进行了回顾性随访研究。共审查了 376 份研究病历。通过审查病历收集数据。将数据输入 Epi-data manager 4.6.0.4 版并通过 Stata 16 版进行分析。进行了描述性分析。进行了 Kaplan-Meier 生存估计和对数秩检验。采用 Cox 比例风险模型。中位恢复时间为 15 天(IQR:6-30),总康复率为每 100 人日 4.49 人。在 cox 比例风险回归中,诊断类别 {AHR: 1.690, 95% CI: (1.150- 2.485)},血氧饱和度 {AHR: 1.600, 95% CI: (1.157- 2.211)},存在合并症 {AHR: 1.774, 95% CI: (1.250–2.519)}、格拉斯哥昏迷评分 {AHR: 2.451, 95% CI: (1.483- 4.051)} 和使用气管切开术 {AHR: 0.276, 95% CI: (0.180–0.422)}具有统计学意义的预测因子。根据本研究的结果,讨论了建议的可能原因及其影响。机械通气患者的持续时间和康复率低于世界卫生组织标准的预期。诊断类别、氧饱和度、合并症、格拉斯哥昏迷量表和气管切开术的使用是具有统计学意义的预测因子。
更新日期:2022-07-13
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