Critical roles for CCR2 and the therapeutic potential of cenicriviroc in periodontitis: A pre-clinical study,Journal of Clinical Periodontology

当前位置： X-MOL 学术 › J. Clin. Periodontol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Critical roles for CCR2 and the therapeutic potential of cenicriviroc in periodontitis: A pre-clinical study
Journal of Clinical Periodontology ( IF 6.7 ) Pub Date : 2022-07-11 , DOI: 10.1111/jcpe.13699
Wenting Jiang ₁ , Tao Xu ₂ , Shasha Yuan ₁ , Yiping Wei ₁ , Zhanming Song ₃ , Qingqing Li ₃ , Shaoping She ₄ , Xuekang Wang ₃ , Cui Wang ₁ , Gang Yang ₁ , Jie Cao ₁ , Fei Sun ₁ , Meng Shi ₅ , Siqi Li ₁ , Zhongtian Liu ₃ , Yaqian Mo ₃ , Ping Lv _{3,

6} , Yu Zhang ₃ , Ying Wang _{3,

6} , Wenjie Hu _{1,

7}

Affiliation

Department of Periodontology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China.
Department of Emergency, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China.
Department of Immunology, School of Basic Medical Sciences, and NHC Key Laboratory of Medical Immunology, Peking University, Beijing, China.
Peking University Hepatology Institute, Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Peking University People's Hospital, Beijing, China.
Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Center for Human Disease Genomics, Peking University, Beijing, China.
NHC Research Center of Engineering and Technology for Computerized Dentistry, Peking University, Beijing, China.

CCR2 plays important roles in many inflammatory and bone metabolic diseases, but its specific role in periodontitis is unknown. In the present study, we aimed to explore the role of CCR2 in the progression of periodontitis and evaluate the effect of cenicriviroc (CVC) on periodontitis.

中文翻译：