Monocryl is a bio-absorbable suture composed of a polyglycolide and poly-epsiloncaprolactone copolymer material and is considered a promising candidate for soft tissues approximation. Consequently, the physical, mechanical, and morphological properties are essential for the surgeons to select the suitable suture for their surgical perform. In this article, Mach Zehnder interferometer equipped with a mechanical drawing device are used for evaluating the mechanical properties and a better understanding of how the Monocryl suture reacts to loading. The two-dimensional fast Fourier transform is applied to extract the phase from the captured interference microinterferograms at different draw ratios. The extracted phase helps to determine some opto-mechanical and structural properties of Monocryle suture. Quantitative structure–activity relationships model is employed for investigating the biological activity of the tested suture. The stress–strain behavior of Monocryl suture has a J-shaped behavior which compatible with the behavior of the soft tissues. The molecular electrostatic potential maps showed that Monocryl model structure is proved to be electrophilic interplays.

中文翻译：

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用于研究用于软组织逼近和结扎的 Monocryl 缝合线的光学和机械性能的相位估计

Monocryl 是一种由聚乙交酯和聚ε-己内酯共聚物材料组成的生物可吸收缝合线，被认为是软组织近似的有希望的候选者。因此，物理、机械和形态特性对于外科医生选择合适的缝合线以进行手术是必不可少的。在本文中，配备机械绘图装置的 Mach Zehnder 干涉仪用于评估机械性能，并更好地了解 Monocryl 缝合线对载荷的反应。应用二维快速傅里叶变换从不同绘制比下捕获的干涉微干涉图中提取相位。提取的相有助于确定 Monocryle 缝合线的一些光学机械和结构特性。定量构效关系模型用于研究测试缝合线的生物活性。Monocryl缝合线的应力-应变行为具有与软组织行为相容的J形行为。分子静电势图表明，Monocryl模型结构被证明是亲电相互作用。