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Taming the transposon: H3K9me3 turns foe to friend in human development
Cell Stem Cell ( IF 23.9 ) Pub Date : 2022-07-07 , DOI: 10.1016/j.stem.2022.06.010
Alisha Chitrakar 1 , Mackenzie Noon 1 , Andrew Zhuo Xiao 1
Affiliation  

In this issue of Cell Stem Cell, Xu et al. and Yu et al. use low-input epigenetic profiling techniques to map H3K9me3 deposition in early human development. They reveal stage-specific H3K9me3 deposition on retrotransposons, which may play crucial cis-regulatory roles in early development.



中文翻译:

驯服转座子:H3K9me3 在人类发展中化敌为友

在本期《细胞干细胞》中,Xu 等人。和余等人。使用低输入表观遗传分析技术来绘制早期人类发育中的 H3K9me3 沉积图。他们揭示了逆转录转座子上阶段特异性的 H3K9me3 沉积,这可能在早期发育中发挥关键的顺式调节作用。

更新日期:2022-07-08
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