Background The prevalence of obesity (body mass index (BMI ≥30)) among nursing home (NH) residents has been increasing, but there has been little research on weight change in this population. We examined resident characteristics associated with substantial weight loss among NH residents with obesity. Methods Using data from the MDS 3.0, this retrospective study included long-stay NH residents with obesity newly admitted to a facility in 2014 who had annual assessments in 2015. Substantial weight loss was defined as a loss of ≥10% body weight within a year. Multivariate regression analyses were conducted to identify factors associated with weight loss, including demographic characteristics, medical conditions, and functional limitations in activities of daily living (ADL). Results Among 59,782 newly admitted NH residents with obesity, 23% experienced substantial weight loss during their first year in the NH. Moderate ADL dependency (OR=1.42, 95% CI: 1.31-1.53), severe ADL dependency (OR=1.83; 95% CI: 1.67-1.99), severe mobility impairment (OR=1.15; 95% CI: 1.04-1.23), and severe cognitive impairment (OR=1.13; 95% CI: 1.07-1.19), as well as cancer (OR=1.10; 95% CI: 1.01-1.20), heart failure (OR=1.06; 95% CI: 1.01-1.11), end-stage renal disease (OR=1.17; 95% CI: 1.11-1.23), and bowel incontinence (OR=1.19; 95% CI: 1.14-1.25) were associated with weight loss. Conclusions Substantial weight loss is common among NH residents with obesity over a one-year period following admission, and these residents have a greater burden of functional and cognitive impairment and specific medical conditions. These findings suggest the need to further elucidate the clinical implications of weight loss among this population.

中文翻译：

---

新入院的肥胖疗养院居民的体重减轻

背景 疗养院 (NH) 居民的肥胖（体重指数 (BMI ≥ 30)）患病率一直在增加，但关于该人群体重变化的研究很少。我们检查了新罕布什尔州肥胖居民中与显着体重减轻相关的居民特征。方法 使用 MDS 3.0 中的数据，这项回顾性研究纳入了 2014 年新入院的肥胖长期住宿 NH 居民，他们在 2015 年进行了年度评估。体重大幅减轻的定义是一年内体重减轻 ≥ 10% . 进行多变量回归分析以确定与体重减轻相关的因素，包括人口特征、医疗条件和日常生活活动 (ADL) 中的功能限制。结果 在 59,782 名新入院的 NH 肥胖居民中，23% 的人在 NH 的第一年经历了显着的体重减轻。中度 ADL 依赖（OR=1.42，95% CI：1.31-1.53​​），严重 ADL 依赖（OR=1.83；95% CI：1.67-1.99），严重行动障碍（OR=1.15；95% CI：1.04-1.23）和严重认知障碍（OR=1.13；95% CI：1.07-1.19），以及癌症（OR=1.10；95% CI：1.01-1.20）、心力衰竭（OR=1.06；95% CI：1.01- 1.11）、终末期肾病（OR=1.17；95% CI：1.11-1.23）和大便失禁（OR=1.19；95% CI：1.14-1.25）与体重减轻相关。结论 入院后一年内肥胖的新罕布什尔州居民体重明显下降很常见，这些居民有更大的功能和认知障碍负担以及特定的医疗条件。