Background

Children presenting with complex febrile seizures (FS) have an increased risk of developing epilepsy. This study aimed to investigate the occurrence of complex seizures in children presenting with FS and those with both convulsions associated with mild gastroenteritis (CwG) and fever.

Methods

Children admitted to our Pediatric Emergency Department between January 2017 and April 2019 with seizures were enrolled in this cross-sectional study. Patients were grouped according to the etiology as FS and febrile CwG. FS classification criteria of simple FS and complex FS was applied to both groups to allow a comparison between them. Prevalence ratios (PRs) of complex seizures, estimated through a log binomial model, were used to compare the occurrence of complex seizures between the two groups, using the FS group as reference category.

Results

A total of 294 patients were enrolled: 231 with FS and 63 with febrile CwG. Complex seizures occurred in 31 patients with FS (13.4%) and 21 patients (33.3%) with febrile CwG. The PR of complex seizures was 2.48 (95% confidence interval, 1.54 to 4.01).

Conclusions

Children with febrile CwG showed a higher rate of complex seizures when compared with those with FS.

中文翻译：

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与轻度胃肠炎相关的高热惊厥和高热惊厥的比较研究

背景

患有复杂性热性惊厥 (FS) 的儿童患癫痫的风险增加。本研究旨在调查患有 FS 的儿童以及伴有轻度胃肠炎 (CwG) 和发烧的惊厥的儿童中复杂癫痫发作的发生情况。

方法

这项横断面研究招募了 2017 年 1 月至 2019 年 4 月期间在我们儿科急诊科住院的癫痫发作儿童。患者根据病因分为 FS 和发热 CwG。将简单 FS 和复杂 FS 的 FS 分类标准应用于两组，以便在它们之间进行比较。通过对数二项式模型估计的复杂癫痫发作的患病率 (PRs) 用于比较两组之间复杂癫痫发作的发生率，使用 FS 组作为参考类别。

结果

共有 294 名患者入组：231 名 FS 和 63 名发热 CwG。31 名 FS 患者（13.4%）和 21 名发热 CwG 患者（33.3%）发生了复杂性癫痫发作。复杂癫痫发作的 PR 为 2.48（95% 置信区间，1.54 至 4.01）。

结论

与患有 FS 的儿童相比，患有发热 CwG 的儿童表现出更高的复杂性癫痫发作率。