Hypertensive disorders of pregnancy affect up to 8% of pregnancies, but updated national trends are lacking. We performed a repeated cross-sectional analysis of individuals with singleton pregnancies who delivered at greater than 20 weeks of gestation, with data in the U.S. National Vital Statistics System from 1989 to 2020. Temporal trends in hypertensive disorders of pregnancy, chronic hypertension, and eclampsia were characterized using joinpoint regression. Overall, 122,329,914 deliveries were included. Hypertensive disorders of pregnancy increased from 2.79% in 1989 to 8.22% in 2020, representing an average annual percentage change (AAPC) of 3.6% (95% CI 3.0-4.1%). Chronic hypertension increased (AAPC 4.1%, 95% CI 3.3-4.9%), whereas eclampsia decreased (AAPC -2.5%, 95% CI -4.0% to -1.0%). Hypertensive disorders of pregnancy are associated with significant morbidity and mortality; the rising incidence is concerning.

中文翻译：

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1989 年至 2020 年美国妊娠期高血压疾病趋势。

妊娠期高血压疾病影响高达 8% 的妊娠，但缺乏最新的全国趋势。我们对妊娠超过 20 周分娩的单胎妊娠个体进行了重复横断面分析，数据来自 1989 年至 2020 年美国国家生命统计系统。妊娠期高血压疾病、慢性高血压和子痫的时间趋势使用连接点回归来表征。总共包括 122,329,914 次交付。妊娠高血压疾病从1989年的2.79%增加到2020年的8.22%，平均年百分比变化（AAPC）为3.6%（95% CI 3.0-4.1%）。慢性高血压增加（AAPC 4.1%，95% CI 3.3-4.9%），而子痫减少（AAPC -2.5%，95% CI -4.0% 至 -1.0%）。妊娠期高血压疾病与显着的发病率和死亡率相关；发病率上升令人担忧。