Maternal–fetal consequences of exposure to blue-wavelength light are poorly understood. This study tested the hypothesis that evening blue-light exposure is associated with maternal fasting glucose and infant birthweight. Forty-one pregnant women (body mass index = 32.90 ± 6.35 kg/m²; 24–39 years old; 16 with gestational diabetes mellitus [GDM]) wore actigraphs for 7 days, underwent polysomnography, and completed study questionnaires during gestational week 30 ± 3.76. Infant birthweight (n = 41) and maternal fasting glucose (n = 30; range = 16–36 weeks) were recorded from the mothers’ medical charts. Blue-light exposure was obtained from Actiwatch-Spectrum recordings. Adjusted and unadjusted linear regression analyses were performed to determine sleep characteristics associated with maternal fasting glucose and infant-birthweight. The mean fasting mid- to late-gestation glucose was 95.73 ± 24.68 mg/dl and infant birthweight was 3271 ± 436 g. In unadjusted analysis, maternal fasting glucose was associated with blue-light exposure (β = 3.82, p = 0.03). In the final model of multiple linear regression for fasting glucose, evening blue-light exposure (β = 4.00, p = 0.01) remained significant after controlling for gestational weight gain, parity, sleep duration, and GDM. Similarly, blue-light exposure was associated with infant birthweight (69.79, p = 0.006) in the unadjusted model, and remained significant (β = 70.38, p = 0.01) after adjusting for weight gain, wakefulness after sleep onset, gestational age at delivery, and GDM. Higher blue-light exposure in pregnancy is associated with higher fasting glucose and infant birthweight. Reduced use of electronic devices before bedtime is a modifiable behavior.

中文翻译：

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夜间蓝光暴露、母体血糖和婴儿出生体重

人们对暴露于蓝色波长光下的母胎后果知之甚少。本研究检验了夜间蓝光暴露与母体空腹血糖和婴儿出生体重相关的假设。41 名孕妇（体重指数 = 32.90 ± 6.35 kg/m ²；24-39 岁；16 名患有妊娠期糖尿病 [GDM]）佩戴活动记录仪 7 天，接受多导睡眠监测，并在妊娠第 30 周完成研究问卷± 3.76。婴儿出生体重 ( n = 41) 和产妇空腹血糖 ( n= 30; 范围 = 16-36 周）是从母亲的病历中记录下来的。蓝光曝光是从 Actiwatch-Spectrum 记录中获得的。进行调整和未调整的线性回归分析以确定与母亲空腹血糖和婴儿出生体重相关的睡眠特征。妊娠中期至晚期的平均空腹血糖为 95.73 ± 24.68 mg/dl，婴儿出生体重为 3271 ± 436 g。在未经调整的分析中，母体空腹血糖与蓝光暴露相关（β = 3.82，p = 0.03）。在最终的空腹血糖多元线性回归模型中，夜间蓝光暴露 ( β = 4.00, p= 0.01) 在控制妊娠期体重增加、胎次、睡眠时间和 GDM 后仍然显着。同样，在未经调整的模型中，蓝光暴露与婴儿出生体重 (69.79，p = 0.006) 相关，并且在调整体重增加、入睡后觉醒、分娩胎龄后仍然显着 ( β = 70.38，p = 0.01) , 和 GDM。怀孕期间较高的蓝光暴露与较高的空腹血糖和婴儿出生体重有关。睡前减少使用电子设备是一种可以改变的行为。