Abstract

Objective

To evaluate whether maternal vitamin D levels affect cord blood Anti Müllerian Hormone (AMH) levels, reflecting ovarian reserve, in female offspring.

Methods

Cord blood AMH from healthy pregnant women delivering term female infants were compared in groups with different maternal vitamin D levels.

Results

Maternal age, weight gain during pregnancy, usage of vitamin D supplements, newborn birth weight, and 5th-min Apgar scores were significantly higher in the normal vitamin D level group (All p < 0.05). AMH levels were similar among all groups (p = 0.6). There was no significant correlation between newborn AMH and maternal vitamin D levels (rho = 0.006, p = 0.9). The stepwise regression analysis showed that the maternal age and birth weight had lower AMH levels, whereas the maternal vitamin D level did not. (p = 0.03, p = 0.04, p = 0.5, respectively).

Conclusion

Maternal vitamin D levels did not have a significant effect on AMH, a reflection of ovarian reserve.

中文翻译：

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母体维生素 D 水平会影响女新生儿的卵巢储备吗？

摘要

客观的

评估母体维生素 D 水平是否影响女性后代脐带血抗苗勒管激素 (AMH) 水平，反映卵巢储备。

方法

在不同母体维生素 D 水平的组中比较来自健康孕妇分娩足月女婴的脐带血 AMH。

结果

维生素 D 水平正常组的产妇年龄、孕期体重增加、维生素 D 补充剂的使用、新生儿出生体重和第 5 分钟 Apgar 评分显着较高（所有p  < 0.05）。所有组的 AMH 水平相似（p  = 0.6）。新生儿 AMH 与母体维生素 D 水平之间没有显着相关性（rho  = 0.006，p  = 0.9）。逐步回归分析表明，母亲年龄和出生体重的AMH水平较低，而母亲维生素D水平则不然。（分别为p  = 0.03、p  = 0.04、p  = 0.5）。

结论

母体维生素 D 水平对 AMH（卵巢储备的反映）没有显着影响。