Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload highlights the potential of such biomaterials for treating a variety of conditions. The translucency of eyes and advances of laser technology in ophthalmology make light-responsive delivery of drugs feasible. Importantly, light can be applied in a non-invasive fashion; therefore, light-triggered drug delivery systems have great potential for clinical impact. This review will examine various types of light-responsive polymers and the chemistry that underpins their application as ophthalmic drug delivery systems.

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用于眼部药物输送的光响应生物材料

光响应生物材料可用于治疗药物和核酸的输送，其中有效负载的可调/精确输送凸显了此类生物材料治疗各种病症的潜力。眼睛的半透明性和眼科激光技术的进步使得光响应药物输送成为可能。重要的是，光可以以非侵入性的方式应用；因此，光触发药物输送系统具有巨大的临床影响潜力。本综述将研究各种类型的光响应聚合物及其作为眼科药物输送系统应用的化学基础。

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