Many approved drugs, including antivirals, are small-molecule inhibitors of disease-causing proteins. Such inhibitors often elicit resistance during treatment. Chaturvedi et al. propose new, feedback-disruptor (FD) antivirals that efficiently cure infected cells from viruses and minimize the chance of resistance, providing a new paradigm to treat viral infections and possibly other diseases.

中文翻译：

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新的抗病毒药物利用病毒反馈技巧实现无耐药性治愈

许多批准的药物，包括抗病毒药物，都是致病蛋白的小分子抑制剂。此类抑制剂通常会在治疗期间引起耐药性。Chaturvedi 等人。提出新的反馈干扰 (FD) 抗病毒药物，可有效治愈受病毒感染的细胞并最大限度地减少耐药性，为治疗病毒感染和可能的其他疾病提供新范例。