Toluene diisocyanate (TDI) is a highly reactive isocyanate commonly used as a mixture of 2,4- and 2,6- isomers in the production of flexible foams. Exposure to TDI occurs primarily through vapour inhalation in workplaces where TDI is produced or used, but dermal exposure is also possible during some tasks. To ensure workplace safety, accurate monitoring of TDI and toluene diamine (TDA) levels is required. Methods of quantifying field effectiveness of gloves in preventing dermal exposure have not been established. Therefore, there is a need to develop a new practical method for assessing glove effectiveness for TDI/TDA.

中文翻译：

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开发一种新的 SPE UPLC-MS/MS 方法，用于萃取和定量接触甲苯二异氰酸酯后手套上的甲苯二胺

甲苯二异氰酸酯 (TDI) 是一种高反应性异氰酸酯，通常用作软质泡沫生产中的 2,4- 和 2,6- 异构体的混合物。在生产或使用 TDI 的工作场所，接触 TDI 主要是通过吸入蒸气，但在某些任务中也可能发生皮肤接触。为确保工作场所安全，需要准确监测 TDI 和甲苯二胺 (TDA) 水平。尚未建立量化手套在防止皮肤暴露方面的现场有效性的方法。因此，需要开发一种新的实用方法来评估手套对 TDI/TDA 的有效性。