With the development of wearable devices, the fabrication of strong, tough, antibacterial, and conductive hydrogels for sensor applications is necessary but remains challenging. Here, a skin-inspired biomimetic strategy integrated with in-situ reduction has been proposed. The self-assembly of cellulose to generate a cellulose skeleton was essential to realize the biomimetic structural design. Furthermore, in-situ generation of silver nanoparticles on the skeleton was easily achieved by a heating process. This process not only offered the excellent antibacterial property to hydrogels, but also improved the mechanical properties of hydrogels due to the elimination of negative effect of silver nanoparticles aggregation. The highest tensile strength and toughness could reach 2.0 MPa and 11.95 MJ/m³, respectively. Moreover, a high detection range (up to 1300%) and sensitivity (gauge factor = 4.4) was observed as the strain sensors. This study provides a new horizon to fabricate strong, tough and functional hydrogels for various applications in the future.

随着可穿戴设备的发展，为传感器应用制造坚固、坚韧、抗菌和导电的水凝胶是必要的，但仍然具有挑战性。在这里，已经提出了一种与原位还原相结合的皮肤启发仿生策略。纤维素的自组装生成纤维素骨架对于实现仿生结构设计至关重要。此外，现场通过加热过程很容易在骨架上生成银纳米颗粒。该工艺不仅为水凝胶提供了优异的抗菌性能，而且由于消除了银纳米粒子聚集的负面影响，提高了水凝胶的力学性能。最高抗拉强度和韧性分别可以达到2.0 MPa和11.95 MJ/m ³。此外，作为应变传感器，观察到高检测范围（高达 1300%）和灵敏度（测量因子 = 4.4）。这项研究为未来制造用于各种应用的坚固、坚韧和功能性水凝胶提供了新的视野。