Synthesizing novel MOFs derived carbon-based materials and investigating their sensing application own important scientific significance. In this work, Zn-MOF (ZIF-8) derived porous carbon with different dimension and atoms doping were facilely prepared via simple MOFs routes. Compared with the widely studied ZIF-8 derived three-dimensional porous N-doped carbon polyhedron frames (N-doped CPF), the two-dimensional porous N-doped carbon nanosheets (N-doped CNS) displayed remarkably enhanced electrochemical sensing performance for its stronger electron transfer ability. On the basis of N-doped carbon materials, the introduction of heteroatom P was also confirmed to be able to further boost their electrochemical activity for the promoted electrochemically active specific surface and interface interaction with the target molecules. As a result, ZIF-8 nanosheets derived N, P-codoped CNS was demonstrated to be qualified for the sensitive detection of various target analytes, including biological molecules (8-hydroxy-2′-deoxyguanosine and guanine), food additive (sunset yellow) and organic pesticide (benomyl). The linear response ranges were 2.5–1000 nM for 8-hydroxy-2′-deoxyguanosine, 50–3500 nM for guanine, 5.0–2000 nM for sunset yellow and 25–2000 nM for benomyl. Besides, their detection limits were as low as 0.85 nM, 14.50 nM, 2.15 nM and 7.50 nM with sensitivity of 950.00 µA μM⁻¹ cm⁻², 52.43 µA μM⁻¹ cm⁻², 527.14 µA μM⁻¹ cm⁻² and 381.43 µA μM⁻¹ cm⁻² for 8-hydroxy-2′-deoxyguanosine, guanine, sunset yellow and benomyl, respectively. Considering the huge application potential of two-dimensional carbon nanosheets, it is believed that the newly synthesized N, P-codoped CNS can play a much greater role for other applications.

合成新型MOFs衍生的碳基材料并研究其传感应用具有重要的科学意义。在这项工作中，通过以下方法轻松制备了不同尺寸和原子掺杂的 Zn-MOF (ZIF-8) 衍生多孔碳。简单的 MOF 路线。与广泛研究的ZIF-8衍生的三维多孔N掺杂碳多面体框架（N掺杂CPF）相比，二维多孔N掺杂碳纳米片（N掺杂CNS）表现出显着增强的电化学传感性能。电子转移能力更强。在N掺杂碳材料的基础上，杂原子P的引入也被证实能够进一步提高其电化学活性，从而促进与目标分子的电化学活性比表面和界面相互作用。结果表明，ZIF-8 纳米片衍生的 N、P 共掺杂 CNS 可用于灵敏检测各种目标分析物，包括生物分子（8-羟基-2'-脱氧鸟苷和鸟嘌呤），食品添加剂（夕阳黄）和有机农药（苯菌灵）。8-羟基-2'-脱氧鸟苷的线性响应范围为 2.5-1000 nM，鸟嘌呤为 50-3500 nM，日落黄为 5.0-2000 nM，苯菌灵为 25-2000 nM。此外，它们的检测限低至 0.85 nM、14.50 nM、2.15 nM 和 7.50 nM，灵敏度为 950.00 µA µM^-1 cm ^-2 , 52.43 µA µM ^-1 cm ^-2 , 527.14 µA µM ^-1 cm ^-2和 381.43 µA µM ^-1 cm ^-2分别用于 8-羟基-2'-脱氧鸟苷、鸟嘌呤、日落黄和苯菌灵. 考虑到二维碳纳米片的巨大应用潜力，相信新合成的N、P共掺杂CNS可以在其他应用中发挥更大的作用。