Abstract

New series of thermo-pH multi-responsive terpolymers were fabricated. Cationic acrylate monomer was synthesized and named by [2-((ditert-butylamino)methyl)-4-formyl-6-methoxyphenyl acrylate] and abbreviated as (DTBAVA). ¹H NMR and ¹³C NMR investigated the new compounds and FT IR. The new terpolymers were fabricated by the free radical polymerization of N-isopropylacrylamide NIPAAm, 10 mol% N, N-dimethylacrylamide and 5, 10, and 20 mol% DTBAVA. The investigation process involved the chemical method such as ¹H NMR and FT IR; physical methods for the solid terpolymers as glass temperature by DSC, polymer degradation by TGA, and polymer crystallinity via XRD. GPC was performed for molecular weights and dispersity; contact angles for identifying the hydrophilic or hydrophobic terpolymers solutions. The lower critical solution temperatures T_c,s, and cloud points C_p^,_s of terpolymers were recorded considering the impact of pH solutions and the concentrations of different sodium salts of (SO₄⁻², Cl⁻¹, and SCN⁻¹) in the Hofmeister series; turbidity measurements were used via UV/vis spectroscopy and micro-DSC. In a new optimization study, we will use these terpolymers in the post-polymerization with biomolecules such as chitosan, protein, and amino acids via Schiff base.

Graphical Abstract

中文翻译：

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pH/盐浓度对调节聚（NIPAAm-co-DMAA-co-DTBAVA）多环境三元共聚物的下临界溶液温度的影响

摘要

制造了新系列的热-pH 多响应三元共聚物。合成阳离子丙烯酸酯单体，命名为[2-((二叔丁基氨基)甲基)-4-甲酰基-6-甲氧基苯基丙烯酸酯]，简称(DTBAVA)。¹ H NMR 和¹³ C NMR 研究了新化合物和FT IR。新的三元共聚物是通过N-异丙基丙烯酰胺 NIPAAm、10 mol% N、N-二甲基丙烯酰胺和 5、10 和 20 mol% DTBAVA的自由基聚合制备的。调查过程涉及化学方法如¹H NMR和FT IR；固体三元共聚物的物理方法如 DSC 的玻璃温度、TGA 的聚合物降解和 XRD 的聚合物结晶度。对分子量和分散性进行 GPC；用于识别亲水或疏水三元共聚物溶液的接触角。^考虑到pH溶液_和⁽ SO _{4 -2 、} Cl ^-1和SCN -1) 在霍夫迈斯特系列中；浊度测量通过紫外/可见光谱和微型 DSC 进行。在一项新的优化研究中，我们将使用这些三元共聚物通过席夫碱与壳聚糖、蛋白质和氨基酸等生物分子进行后聚合。

图形概要