North-Eastern Italy and in particular Veneto Region, stands out as a major centre of agriculture and viticulture which has rapidly expanded in the last decade with high productivity indexes. In this context, assessing atmospheric pollution caused by crop spraying with pesticides in rural areas and their transport to high-altitude remote sites is crucial to provide a basis for understanding possible impacts on the environment and population health. We aim to improve existing methods with a highly sensitive technique by using high pressure anion exchange chromatography coupled to a triple quadrupole mass spectrometer. Thus, a total of fourteen polar pesticides were determined in aerosol samples collected from August to December 2021 at Roncade (Venetian plain) and Col Margherita Observatory (Dolomites). The observatory was chosen as the background site as it is representative of the surrounding alpine region. Some samples revealed a substantial amount of cyanuric acid mainly at Roncade (mean concentration of 10 ± 10 ng m⁻³), glyphosate and fosetyl-aluminium (0.1 ± 0.2 and 0.1 ± 0.1 ng m⁻³, respectively). Surprisingly, some pesticides have been also found at Col Margherita, a high mountain background site, with concentrations an order of magnitude lower than at Roncade. This is the first time that fourteen polar pesticides have been assessed in the aerosol phase of the Po’ Valley and detected at a high-altitude remote site, and consequently this study provides the first data on their occurrences in Italian aerosols. It represents a basis for the assessment of risks for humans.

意大利东北部，特别是威尼托大区，作为农业和葡萄种植的主要中心而脱颖而出，在过去十年中迅速扩张，生产力指数很高。在这种情况下，评估农村地区农作物喷洒杀虫剂及其运输到高海拔偏远地区造成的大气污染对于了解可能对环境和人口健康造成的影响至关重要。我们的目标是通过使用与三重四极杆质谱仪耦合的高压阴离子交换色谱，以高灵敏度技术改进现有方法。因此，在 2021 年 8 月至 2021 年 12 月在 Roncade（威尼斯平原）和 Col Margherita 天文台（白云岩）采集的气溶胶样品中，总共测定了 14 种极性农药。天文台被选为背景站点，因为它代表了周围的高山地区。一些样品显示大量的氰尿酸主要在 Roncade（平均浓度为 10 ± 10 ng m^-3 )、草甘膦和乙膦铝（分别为 0.1 ± 0.2 和 0.1 ± 0.1 ng m ^-3）。令人惊讶的是，在高山背景地点 Col Margherita 也发现了一些杀虫剂，其浓度比 Roncade 低一个数量级。这是第一次在波谷的气溶胶阶段评估并在高海拔偏远地区检测到 14 种极性农药，因此这项研究提供了有关它们在意大利气溶胶中出现的第一个数据。它是评估人类风险的基础。