Bromination is herein exploited to promote the emergence of elastic behavior in a short peptide—SDSYGAP—derived from resilin, a rubber-like protein exerting its role in the jumping and flight systems of insects. Elastic and resilient hydrogels are obtained, which also show self-healing behavior, thanks to the promoted non-covalent interactions that limit deformations and contribute to the structural recovery of the peptide-based hydrogel. In particular, halogen bonds may stabilize the β-sheet organization working as non-covalent cross-links between nearby peptide strands. Importantly, the unmodified peptide (i.e., wild type) does not show such properties. Thus, SDSY(3,5-Br)GAP is a novel minimalist peptide elastomer.

中文翻译：

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溴化后极简树脂衍生七肽弹性特性的出现

本文利用溴化作用来促进短肽 SDSYGAP 中弹性行为的出现，该短肽源自弹性蛋白，弹性蛋白是一种在昆虫的跳跃和飞行系统中发挥作用的橡胶状蛋白质。由于促进的非共价相互作用限制了变形并有助于肽基水凝胶的结构恢复，因此获得了具有弹性和弹性的水凝胶，它们也显示出自修复行为。特别是，卤素键可以稳定β-折叠组织，作为附近肽链之间的非共价交联。重要的是，未修饰的肽（即野生型）不显示这种特性。因此，SDSY(3,5-Br)GAP 是一种新型的极简肽弹性体。