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Plant hormone sensors as scaffolds for biosensor design
Nature Biotechnology ( IF 46.9 ) Pub Date : 2022-06-20 , DOI: 10.1038/s41587-022-01373-4


Most plant hormone sensors, including the abscisic acid receptor PYR1, function through chemically induced dimerization. Using computationally designed libraries of PYR1, we created high-affinity receptors for 21 structurally diverse ligands, setting the stage for large-scale small-molecule biosensor development

中文翻译:

植物激素传感器作为生物传感器设计的支架

大多数植物激素传感器,包括脱落酸受体 PYR1,都通过化学诱导的二聚作用发挥作用。使用计算设计的 PYR1 库,我们为 21 种结构多样的配体创建了高亲和力受体,为大规模小分子生物传感器开发奠定了基础
更新日期:2022-06-20
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