Amyopathic dermatomyositis (ADM) is a heterogeneous and life-threatening autoimmune disease with a high mortality rate. In particular, anti–melanoma differentiation–associated protein 5 antibody–positive patients are at a high risk of developing rapidly progressive interstitial lung disease (RPILD). This study was undertaken to identify immunologic signatures among patients who have ADM with ILD (ADM-ILD) and to discover the biomarkers predicting prognosis.

中文翻译：

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两种不同的免疫细胞特征预测无肌病性皮肌炎伴间质性肺病患者的临床结果

无肌病性皮肌炎 (ADM) 是一种异质性、危及生命的自身免疫性疾病，死亡率很高。特别是，抗黑色素瘤分化相关蛋白 5 抗体阳性的患者患快速进展性间质性肺病 (RPILD) 的风险很高。本研究旨在确定 ADM 伴 ILD (ADM-ILD) 患者的免疫学特征，并发现预测预后的生物标志物。