Plasminogen activator inhibitor-1 (PAI-1) is significantly enhanced in insulin resistance and inflammation and ascribed as a proinflammatory marker. This study aimed to compare and correlate salivary and serum PAI-1 and alpha 2-macroglobulin (α2MG) in patients with periodontitis with and without type 2 diabetes mellitus (T2DM) and also appraise the consequence of periodontal treatment on these biomarkers.

中文翻译：

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刮治和根面平整对合并和不合并 2 型糖尿病的牙周炎患者唾液和血清纤溶酶原激活物抑制因子-1 表达的影响

Plasminogen activator inhibitor-1 (PAI-1) 在胰岛素抵抗和炎症方面显着增强，并被认为是促炎标志物。本研究旨在比较和关联伴有和不伴有 2 型糖尿病 (T2DM) 的牙周炎患者的唾液和血清 PAI-1 和 α2-巨球蛋白 (α2MG)，并评估牙周治疗对这些生物标志物的影响。