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Reconsidering the Safety Hazards Associated with Peroxide Formation in 2-Propanol
Organic Process Research & Development ( IF 3.4 ) Pub Date : 2022-05-31 , DOI: 10.1021/acs.oprd.2c00112
Megan A. Cismesia 1 , Suhelen Vásquez Céspedes 1
Affiliation  

2-Propanol is a common solvent in academic and industrial research laboratories, yet awareness around its classification as a Group B peroxide-forming solvent is lacking. Because of this deficiency, there have been several reports of explosions occurring during the distillation of 2-propanol that have resulted in injury to researchers. This Perspective discusses the historical literature around 2-propanol as a peroxide former and the potential for quality and safety hazard issues that come from trace peroxides in the solvent. Furthermore, the likelihood of peroxide formation in laboratory samples of 2-propanol is discussed with emphasis on the type of storage conditions.

中文翻译:

重新考虑与 2-丙醇中过氧化物形成相关的安全危害

2-丙醇是学术和工业研究实验室中的常用溶剂,但对其分类为 B 组过氧化物形成溶剂缺乏认识。由于这一缺陷,有几起关于 2-丙醇蒸馏过程中发生爆炸导致研究人员受伤的报告。本观点讨论了有关 2-丙醇作为过氧化物形成剂的历史文献,以及溶剂中痕量过氧化物可能导致的质量和安全隐患问题。此外,还讨论了 2-丙醇实验室样品中形成过氧化物的可能性,重点是储存条件的类型。
更新日期:2022-05-31
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