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Two-dimensional manipulation of droplets on a single-sided continuous optoelectrowetting digital microfluidic chip
Sensors and Actuators B: Chemical ( IF 8.4 ) Pub Date : 2022-06-16 , DOI: 10.1016/j.snb.2022.132231
Enqing Liu , Cui Wang , Hanyun Zheng , Shuren Song , Antoine Riaud , Jia Zhou

Digital microfluidic chips are liquid processors that perform biochemical assays by moving, merging and splitting droplets using the electrowetting effect. Yet, hardwiring electrowetting chips becomes tedious as soon as they include more than a few dozen electrodes. Single-sided continuous opto-electrowetting, where the electrowetting effect of a featureless semiconductor film is controlled by light patterns is a promising solution to this hardwiring bottleneck, but so far two-dimensional manipulation of droplets is still difficult. Here, we demonstrate the manipulation of droplets along arbitrary directions by using Z-shaped light patterns that rotate the electric field by an arbitrary angle. We provide a theoretical model for driving droplets in different directions. It is verified by Comsol simulations and experiments. Optimization of the width of the notches provides quite large increase of the driving voltage in the y-direction. The chip can move dyed water droplets in the y-direction at a maximum speed of 4.86 mm/s. Such multidimensional droplet driving opens new possibilities for single-sided continuous optoelectrowetting such as merging droplets that are not in line, efficient droplet mixing, and bypassing droplets to avoid coalescence.



中文翻译:

单面连续光电润湿数字微流控芯片上液滴的二维操作

数字微流控芯片是一种液体处理器,通过使用电润湿效应移动、合并和分裂液滴来执行生化分析。然而,一旦它们包含超过几十个电极,硬接线电润湿芯片就会变得乏味。单面连续光电润湿,其中无特征半导体薄膜的电润湿效应由光图案控制,是解决这一硬接线瓶颈的有希望的解决方案,但到目前为止,液滴的二维操作仍然很困难。在这里,我们演示了通过使用将电场旋转任意角度的 Z 形光图案沿任意方向操纵液滴。我们提供了一个用于在不同方向上驱动液滴的理论模型。它通过 Comsol 模拟和实验得到了验证。槽口宽度的优化提供了y方向上驱动电压的相当大的增加。该芯片可以在 y 方向以 4.86 mm/s 的最大速度移动染色水滴。这种多维液滴驱动为单面连续光电润湿开辟了新的可能性,例如合并不在线的液滴、有效的液滴混合以及绕过液滴以避免聚结。

更新日期:2022-06-16
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