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Visible-Light-Promoted Cross Dehydrogenative/Decarboxylative Coupling Cascades of Glycine Ester Derivatives and β-Keto Acids
The Journal of Organic Chemistry ( IF 3.6 ) Pub Date : 2022-06-15 , DOI: 10.1021/acs.joc.2c00149
Chunhui Jiang 1 , Xuefei Sha 1 , Cheng Ni 1 , Wei Qin 1 , Xuejie Zhu 1 , Shan Wang 1 , Xuan Li 1 , Hongfei Lu 1
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A visible-light-induced dehydrogenative/decarboxylative coupling reaction of arylglycine derivatives and β-keto acids is described. This photocatalyst- and additive-free protocol can be applied in the efficient synthesis of γ-keto glycine derivatives under ambient conditions. Further uses of this methodology and a plausible mechanism are also demonstrated.

中文翻译:

可见光促进甘氨酸酯衍生物和β-酮酸的交叉脱氢/脱羧偶联级联

描述了芳基甘氨酸衍生物和β-酮酸的可见光诱导的脱氢/脱羧偶联反应。这种无光催化剂和无添加剂的方案可用于在环境条件下有效合成 γ-酮甘氨酸衍生物。还展示了该方法的进一步使用和合理的机制。
更新日期:2022-06-15
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