Melanoma differentiation-associated gene 5 (MDA5) is a viral RNA sensor induced by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Similarities have been reported between the clinical presentations of coronavirus disease 2019 (COVID-19) pneumonia and anti-MDA5 antibody-positive interstitial lung disease (anti-MDA5-ILD). However, it is unknown whether COVID-19 mRNA vaccines are associated with anti-MDA5-ILD.

中文翻译：

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接种 COVID-19 mRNA 疫苗后抗黑色素瘤分化相关基因 5 抗体阳性间质性肺病。

黑色素瘤分化相关基因 5 (MDA5) 是由严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 诱导的病毒 RNA 传感器。据报道，2019 年冠状病毒病 (COVID-19) 肺炎和抗 MDA5 抗体阳性间质性肺病 (anti-MDA5-ILD) 的临床表现有相似之处。然而，尚不清楚 COVID-19 mRNA 疫苗是否与抗 MDA5-ILD 相关。