The enteric nervous system (ENS), considered as separate branch of the autonomic nervous system, is located throughout the length of the gastrointestinal tract as a series of interconnected ganglionic plexuses. Recently, the ENS is getting more in the focus of gastrointestinal research. For years, the main interest and research was aimed to the enteric neurons and their functional properties in normal conditions, less attention has been paid to the germ-free animals. Germ-free (GF) piglets have clear microbiological background and are reared in sterile environment. GF piglets are regarded as clinically relevant models for studying of human diseases, as these piglets’ manifest similar clinical symptoms to humans. In this study we briefly summarised the main characteristics in immunohistochemical distribution of ENS elements in the wall of jejunum and colon of germ-free piglets.

肠神经系统 (ENS) 被认为是自主神经系统的独立分支，作为一系列相互连接的神经节丛位于整个胃肠道的长度。最近，ENS 越来越成为胃肠道研究的焦点。多年来，主要的兴趣和研究都是针对肠道神经元及其在正常条件下的功能特性，而对无菌动物的关注较少。无菌 (GF) 仔猪具有明确的微生物学背景，并在无菌环境中饲养。GF仔猪被认为是研究人类疾病的临床相关模型，因为这些仔猪表现出与人类相似的临床症状。