Dementia is a syndrome where the origins are not fully understood, and we have no cure. New thinking through exploration of paradigms beyond biological approaches has scope to improve knowledge about this complex condition. We aim to explore the role of social health in cognitive decline and the onset of dementia. We performed a scoping and a systematic review of the literature, hypothesizing that social health acts as a driver for stimulating the use of cognitive reserve. The review yielded theoretical pathways and evidence for the association between neurobiological and social health markers. However, lack of conceptual clarity on social health hinders its articulation and associated inclusion of social health markers in epidemiological studies. We therefore apply concept advancement of social health. We developed a conceptual framework, and we present a first testing of our overarching hypothesis. This framework proved to effectively guide the identification of social health markers in our epidemiological data bases. This promotes the identification of modifiable risk factors, which may in turn shape new avenues for preventive interventions.

中文翻译：

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概念推进：社会健康作为认知储备使用的促进者

痴呆症是一种病因尚不完全清楚的综合症，我们无法治愈。通过探索超越生物学方法的范式的新思维具有提高对这种复杂情况的认识的空间。我们的目标是探索社会健康在认知能力下降和痴呆症发病中的作用。我们对文献进行了范围界定和系统回顾，假设社会健康是刺激认知储备使用的驱动因素。该综述为神经生物学和社会健康标志物之间的关联提供了理论途径和证据。然而，社会健康概念缺乏明确性阻碍了其在流行病学研究中的表达和相关纳入社会健康标志物。因此，我们应用社会健康的概念推进。我们开发了一个概念框架，我们对我们的总体假设进行了第一次测试。事实证明，该框架有效地指导了我们流行病学数据库中社会健康标志物的识别。这促进了对可改变的风险因素的识别，这反过来又可能为预防性干预创造新的途径。