This highlight summarizes a recent development of KF-promoted three-component fluorination-aminocarbonylation reaction of aldehydes, tertiary amines, and TMSCF₂Br for the synthesis of structurally important α-fluoroamide derivatives. The key to the success of this method could be attributed to the multiple functions of difluorocarbene precursor (TMSCF₂Br) as both a C1 synthon and a F1 reagent through the process of C–F bond cleavage and C–F bond re-formation.

中文翻译：

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TMSCF2Br 作为 C1 合成子和 F1 试剂

_{这一亮点总结了 KF 促进的醛、叔胺和 TMSCF 2} Br的三组分氟化-氨基羰基化反应的最新发展，用于合成结构上重要的α-氟酰胺衍生物。该方法成功的关键可归因于二氟卡宾前体 (TMSCF ₂ Br) 通过 C-F 键断裂和 C-F 键重新形成过程作为 C1 合成子和 F1 试剂的多重功能。