Interest is growing in genome-editing tools that can insert large chunks of DNA into the genome — and avoid the double-strand breaks associated with CRISPR–Cas9 genotoxicity.

中文翻译：

---

敲开 CRISPR 的大门

人们对基因组编辑工具越来越感兴趣，这些工具可以将大块 DNA 插入基因组——并避免与 CRISPR-Cas9 基因毒性相关的双链断裂。