Background

Systematic investigation of muscle protein synthesis (MPS) responses with or without protein ingestion has been largely limited to resistance training.

Objective

This systematic review determined the capacity for aerobic-based exercise or high-intensity interval training (HIIT) to stimulate post-exercise rates of MPS and whether protein ingestion further significantly increases MPS compared with placebo.

Methods

Three separate models analysed rates of either mixed, myofibrillar, sarcoplasmic, or mitochondrial protein synthesis (PS) following aerobic-based exercise or HIIT: Model 1 (n = 9 studies), no protein ingestion; Model 2 (n = 7 studies), peri-exercise protein ingestion with no placebo comparison; Model 3 (n = 14 studies), peri-exercise protein ingestion with placebo comparison.

Results

Eight of nine studies and all seven studies in Models 1 and 2, respectively, demonstrated significant post-exercise increases in either mixed or a specific muscle protein pool. Model 3 observed significantly greater MPS responses with protein compared with placebo in either mixed or a specific muscle fraction in 7 of 14 studies. Seven studies showed no difference in MPS between protein and placebo, while three studies reported no significant increases in mitochondrial PS with protein compared with placebo.

Conclusion

Most studies reporting significant increases in MPS were confined to mixed and myofibrillar PS that may facilitate power generating capacity of working skeletal muscle with aerobic-based exercise and HIIT. Only three of eight studies demonstrated significant increases in mitochondrial PS post-exercise, with no further benefits of protein ingestion. This lack of change may be explained by the acute analysis window in most studies and apparent latency in exercise-induced stimulation of mitochondrial PS.

中文翻译：

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有氧运动或高强度间歇训练后有或没有蛋白质摄入的肌肉蛋白质合成反应：系统评价

背景

对摄入或不摄入蛋白质的肌肉蛋白质合成 (MPS) 反应的系统研究主要限于阻力训练。

客观的

该系统评价确定了有氧运动或高强度间歇训练 (HIIT) 刺激运动后 MPS 率的能力，以及与安慰剂相比，蛋白质摄入是否进一步显着增加 MPS。

方法

三个独立的模型分析了有氧运动或 HIIT 后混合、肌原纤维、肌浆或线粒体蛋白质合成 (PS) 的速率：模型 1（n  = 9 项研究），无蛋白质摄入；模型 2（n  = 7 项研究），没有安慰剂比较的围运动期蛋白质摄入；模型 3（n  = 14 项研究），运动前后蛋白质摄入与安慰剂比较。

结果

9 项研究中的 8 项以及模型 1 和 2 中的所有 7 项研究分别表明，混合或特定肌肉蛋白质库在运动后显着增加。在 14 项研究中的 7 项研究中，模型 3 在混合或特定肌肉部分中观察到与安慰剂相比，蛋白质的 MPS 反应显着增强。七项研究显示蛋白质和安慰剂之间的 MPS 没有差异，而三项研究报告与安慰剂相比，蛋白质的线粒体 PS 没有显着增加。

结论

大多数报告 MPS 显着增加的研究仅限于混合和肌原纤维 PS，它们可能通过有氧运动和 HIIT 促进工作骨骼肌的发电能力。八项研究中只有三项表明运动后线粒体 PS 显着增加，而蛋白质摄入没有进一步的好处。这种变化的缺乏可以用大多数研究中的急性分析窗口和运动诱导的线粒体 PS 刺激的明显潜伏期来解释。