A versatile and sustainable approach to one of the most commonly employed families of herbicides has been developed, which is based on a biocatalytic reductive dehalogenation followed by simple chemical manipulations. A range of commercially relevant target molecules have been obtained in good yield and moderate to excellent enantioselectivity (to either enantiomer), without chromatographic purifications and by using crude enzyme preparations.

中文翻译：

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对映体富集 (R)- 和 (S)-芳氧基链烷酸除草剂的化学酶合成

对于最常用的除草剂家族之一，已经开发出一种通用且可持续的方法，该方法基于生物催化还原脱卤，然后进行简单的化学操作。一系列商业相关的目标分子已经以良好的收率和中等至极好的对映选择性（对任一对映异构体）获得，无需色谱纯化和使用粗酶制剂。