Artificial ion channels with tunable ionic transport control and intelligent iontronic functions at the nanoscale have a wide application in logic computing and biosensing. Although some artificial ion channels with smart ion transport characteristics have been developed, most of them are constructed on porous membranes with undefined channel numbers. It is still challenging to achieve multiple ion transport features in single nanochannels and to control the ion flow more accurately with excellent repeatability. In this paper, a design strategy is presented to fabricate pH-responsive ion channels with various ion transport features based on a single polydimethylsiloxane (PDMS) nanochannel. The single-ion nanochannel developed by this approach can be further integrated into electronic systems on a chip. Three types of artificial ion channels are demonstrated and investigated systematically in this work. With symmetric or asymmetric pH stimuli, these ion channels can alternatively change their working states among an opened state, a closed state, and an ionic diode state. Four different ion transport features can be realized in a triple-gated ion channel system. With these advantages of the design, it is promising to build smart nanofluidic iontronic devices with widespread applicability in energy conversions, active ion transport control, and biological analysis.

中文翻译：

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基于 pH 响应聚合物表面改性的具有可调离子传输的单人工离子通道

具有可调谐离子传输控制和纳米级智能离子电子功能的人工离子通道在逻辑计算和生物传感中具有广泛的应用。尽管已经开发了一些具有智能离子传输特性的人工离子通道，但它们大多是在通道数不确定的多孔膜上构建的。在单个纳米通道中实现多种离子传输特征并以出色的可重复性更准确地控制离子流仍然具有挑战性。在本文中，提出了一种设计策略，用于基于单个聚二甲基硅氧烷 (PDMS) 纳米通道制造具有各种离子传输特征的 pH 响应离子通道。通过这种方法开发的单离子纳米通道可以进一步集成到芯片上的电子系统中。在这项工作中系统地展示和研究了三种类型的人工离子通道。通过对称或不对称的 pH 刺激，这些离子通道可以在打开状态、关闭状态和离子二极管状态之间交替改变其工作状态。在三门离子通道系统中可以实现四种不同的离子传输特性。凭借该设计的这些优点，有望构建在能量转换、主动离子传输控制和生物分析中具有广泛应用的智能纳米流体离子电子器件。在三门离子通道系统中可以实现四种不同的离子传输特性。凭借该设计的这些优点，有望构建在能量转换、主动离子传输控制和生物分析中具有广泛应用的智能纳米流体离子电子器件。在三门离子通道系统中可以实现四种不同的离子传输特性。凭借该设计的这些优点，有望构建在能量转换、主动离子传输控制和生物分析中具有广泛应用的智能纳米流体离子电子器件。