Group 2 innate lymphoid cells (ILC2s) are lymphocytes that both promote and suppress antitumor immunity. Jou and colleagues now report in colorectal tumorigenesis that the cytokine interleukin-25 activates ILC2s to induce myeloid cells that suppress antitumor immunity.

中文翻译：

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ILC2s——癌症领域的两党政客

第 2 组先天性淋巴样细胞 (ILC2) 是既能促进又能抑制抗肿瘤免疫的淋巴细胞。Jou 及其同事现在在结直肠肿瘤发生中报告说，细胞因子白介素 25 激活 ILC2 以诱导抑制抗肿瘤免疫的骨髓细胞。