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Internal Validation of a Risk Scoring System for Venous Thromboembolism After Total hip or Knee Arthroplasty
Clinical and Applied Thrombosis/Hemostasis ( IF 2.9 ) Pub Date : 2022-05-31 , DOI: 10.1177/10760296221103868
Akihiko Akamine 1, 2 , Naonobu Takahira 1, 3 , Masayuki Kuroiwa 4 , Atsushi Tomizawa 2 , Koichiro Atsuda 2, 5
Affiliation  

We developed a computerized clinical decision support system (CCDSS) for venous thromboembolism (VTE) risk assessment. We aimed to demonstrate its relevance and evaluate associations between risk level and VTE incidence in patients undergoing total hip/knee arthroplasty. In this case-control study, VTE was confirmed using ultrasonography/computed tomography angiography in 1098 adults at a tertiary care hospital over five years (2013-2018). Postoperative VTE incidence was classified into three risk levels (moderate, high, and highest). The overall VTE incidence was 11.7%, which increased with a risk level of 0%, 5.8%, and 12.8% in moderate-risk, high-risk, and highest-risk patients, respectively. Highest-risk patients were significantly more likely to develop VTE than high-risk patients (odds ratio [OR] 2.4; 95% confidence interval [CI] 1.2-5.5; p = 0.01). VTE development was more likely in patients with risk scores ≥4 relative to those with risk scores of 2–3 (OR 1.8; 95% CI 1.2-2.7; p = 0.003) and −1 to 1 (OR 3.3; 95% CI 1.6-7.7; p < 0.001). This study indicates that risk level and VTE incidence are associated; our scoring system appears useful for patients undergoing total hip/knee arthroplasty.



中文翻译:

全髋或膝关节置换术后静脉血栓栓塞风险评分系统的内部验证

我们开发了一种用于静脉血栓栓塞 (VTE) 风险评估的计算机化临床决策支持系统 (CCDSS)。我们旨在证明其相关性并评估风险水平与接受全髋/膝关节置换术患者的 VTE 发病率之间的关联。在这项病例对照研究中,五年内(2013-2018 年),在一家三级医院的 1098 名成年人中使用超声检查/计算机断层扫描血管造影术证实了 VTE。术后 VTE 发生率分为三个风险等级(中、高和最高)。总体 VTE 发生率为 11.7%,中危、高危和最高危患者的风险水平分别增加 0%、5.8% 和 12.8%。最高风险患者发生 VTE 的可能性显着高于高风险患者(优势比 [OR] 2.4;95% 置信区间 [CI] 1.2-5.5;p = 0.01)。相对于风险评分为 2-3(OR 1.8;95% CI 1.2-2.7;p = 0.003)和 -1 至 1(OR 3.3;95% CI 1.6)的患者,风险评分≥4 的患者更容易发生 VTE -7.7;p < 0.001)。该研究表明风险水平和 VTE 发病率相关;我们的评分系统似乎对接受全髋/膝关节置换术的患者有用。

更新日期:2022-06-05
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