Background: 

In the neonatal intensive care unit (NICU), maintaining an oxygenation level that avoids both hypoxemia and hyperoxemia is challenging. Pulse oximetry has become fundamental for noninvasive monitoring of saturation of peripheral oxygen (Spo₂) in preterm newborns.

Purpose: 

The aim of this systematic review is to determine Spo₂ target values in order to avoid hypoxemia or hyperoxemia and complications arising from these.

Method and Search Strategy: 

For this systematic review, articles were audited from 2010 to 2020 using the PRISMA guidelines. PubMed, MEDLINE, Google Scholar, and Scopus databases were used, and search terms were related to use of pulse oximetry in the NICU.

Results: 

The result showed that 12 of 20 (60%) studies focused on target values but without a unanimous agreement on values, although 5 of 12 studies (41.66%) suggested a lower value target of 85% and 4 of 12 studies (33.33%) recommended 95% as the higher target value. Other authors showed no difference in the incidence of adverse events comparing different target values and focused the importance more on the fluctuation of the value than on the target value itself.

Implication for Practice: 

Reaching a balance in the oxygen administration so as to avoid potential complications associated with hypoxemia or hyperoxemia is a challenge for the clinicians.

Implication for Research: 

Further studies on fluctuation of Spo₂ comparing different starting targets could better clarify the role of fluctuations and the absolute target values.

Video Abstract available at:https://journals.na.lww.com/advancesinneonatalcare/Pages/videogallery.aspx?autoPlay=false&videoId=49

中文翻译：

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新生儿重症监护室 (NICU) 的脉搏血氧饱和度 (Spo2) 监测：提供者面临的挑战：系统评价

背景： 

在新生儿重症监护病房 (NICU) 中，维持避免低氧血症和高氧血症的氧合水平具有挑战性。脉搏血氧仪已成为无创监测早产儿外周血氧饱和度 (Sp o _{2 ) 的基础。}

目的： 

本系统评价的目的是确定 Sp o ₂ 目标值，以避免低氧血症或高氧血症以及由此引起的并发症。

方法和搜索策略： 

对于本系统评价，文章使用 PRISMA 指南从 2010 年到 2020 年进行了审核。使用了 PubMed、MEDLINE、Google Scholar 和 Scopus 数据库，搜索词与 NICU 中脉搏血氧仪的使用有关。

结果： 

结果显示，20 项研究中有 12 项 (60%) 侧重于目标值，但没有就价值达成一致，尽管 12 项研究中有 5 项 (41.66%) 提出了较低的目标值，85% 和 12 项研究中有 4 项 (33.33%)推荐 95% 作为较高的目标值。其他作者在比较不同的目标值时显示不良事件的发生率没有差异，并且将重要性更多地集中在值的波动上而不是目标值本身。

对实践的启示： 

在氧气管理中达到平衡以避免与低氧血症或高氧血症相关的潜在并发症对临床医生来说是一个挑战。

研究意义： 

进一步研究比较不同起始目标的Sp o ₂波动，可以更好地阐明波动的作用和绝对目标值。

视频摘要见：https ://journals.na.lww.com/advancesinneonatalcare/Pages/videogallery.aspx?autoPlay=false&videoId=49