MG8, a novel polyethylene-terephthalate (PET) hydrolase from the human saliva metagenome, with robust PET degradation activity, was discovered and characterized. It was further repurposed into a covalent binder of PET through genetic code expansion, enabling its use to attach protein payloads to PET and other polyesters under mild conditions.

中文翻译：

---

人类唾液宏基因组聚对苯二甲酸乙二醇酯 (PET) 水解酶的发现和遗传密码扩展，用于 PET 的降解和生物功能化

MG8 是一种来自人类唾液宏基因组的新型聚对苯二甲酸乙二醇酯 (PET) 水解酶，具有强大的 PET 降解活性，已被发现并表征。通过遗传密码扩展，它被进一步改造成 PET 的共价粘合剂，使其能够在温和条件下将蛋白质有效载荷附着到 PET 和其他聚酯上。