Herein, a novel solid-phase microextraction (SPME) fiber based on the NU-1000 sorbent was developed for direct immersion extraction of organochlorine pesticides (OCPs) in water samples. As a kind of metal-organic framework, the NU-1000 possessed the mesoporous channels which were beneficial for the mass transfer of target analytes. Extraction equilibrium was achieved rapidly with the optimal extraction time of 30 min. The NU-1000 coated fiber with a high specific surface area showed better extraction efficiencies than commercial fibers (65 μm PDMS/DVB or 85 μm PA) towards OCPs, with the enrichment factors of the NU-1000 coated fiber 2–20 times higher than the latter. NU-1000 coated fiber showed higher extraction efficiencies toward polycyclic aromatic hydrocarbons (PAHs) than OCPs and nitrobenzenes. This indicated that π-π interaction and CH-π interaction between pollutants and aromatic groups of the NU-1000 contributed to the high extraction efficiencies. Under the optimal conditions (extraction at 40 °C for 30 min and desorption at 260 °C for 6 min), the NU-1000 coated fiber coupled with gas chromatography-mass spectrometry (GC-MS) exhibited satisfied analytical performance on analysis of OCPs, with a wide linear range (0.1–2000 ng L⁻¹), low limits of detections (LODs, 0.011–0.058 ng L⁻¹), and good reproducibility and repeatability. The established method has been successfully applied to the determination of OCPs in surface water with good sensitivity and recoveries, which proved the great promise of the NU-1000 on the extraction of organic pollutants with conjugated groups.

在此，开发了一种基于 NU-1000 吸附剂的新型固相微萃取 (SPME) 纤维，用于水样中有机氯农药 (OCP) 的直接浸提萃取。NU-1000作为一种金属有机骨架，具有有利于目标分析物传质的介孔通道。提取平衡迅速达到最佳提取时间为 30 分钟。具有高比表面积的 NU-1000 涂层光纤对 OCPs 的提取效率优于商用光纤（65 μm PDMS/DVB 或 85 μm PA），NU-1000 涂层光纤的富集因子比商用光纤高 2-20 倍。后者。NU-1000 涂层纤维对多环芳烃 (PAH) 的萃取效率高于 OCP 和硝基苯。这表明污染物与 NU-1000 芳香族基团之间的 π-π 相互作用和 CH-π 相互作用有助于提高萃取效率。在最佳条件下（40 °C 萃取 30 min 和 260 °C 解吸 6 min），NU-1000 涂层光纤与气相色谱-质谱联用（GC-MS）对 OCPs 的分析表现出满意的分析性能, 具有较宽的线性范围 (0.1–2000 ng L^-1 )、低检测限 (LODs, 0.011–0.058 ng L ^-1 ) 以及良好的重现性和可重复性。所建立的方法已成功应用于地表水中OCPs的测定，具有良好的灵敏度和回收率，证明了NU-1000在共轭基团提取有机污染物方面的巨大潜力。