Traditional Chinese medicines (TCMs) have been widely used in clinical and healthcare applications around the world. The characterization of the phytochemical components in TCMs is very important for studying the therapeutic mechanism of TCMs. In the analysis process, sample preparation and instrument analysis are key steps to improve analysis performance and accuracy. In recent years, chromatography combined with mass spectrometry (MS) has been widely used for the separation and detection of trace components in complex TCM samples. This article reviews various sample preparation techniques and chromatography-MS techniques, including the application of gas chromatography-MS and liquid chromatography-MS and other MS techniques in the characterization of phytochemicals in TCM materials and Chinese medicine products. This article also describes a new ambient ionization MS method for rapid and high-throughput analysis of TCM components.

中文翻译：

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中药中有效植物化学物质的质谱表征

中药（TCM）已广泛应用于世界各地的临床和医疗保健应用。中药植物化学成分的表征对于研究中药的治疗机制非常重要。在分析过程中，样品制备和仪器分析是提高分析性能和准确性的关键步骤。近年来，色谱结合质谱（MS）已广泛应用于复杂中药样品中微量成分的分离和检测。本文综述了各种样品前处理技术和色谱-质谱技术，包括气相色谱-质谱和液相色谱-质谱等质谱技术在中药材和中药产品中植物化学物质表征中的应用。本文还介绍了一种新的环境电离 MS 方法，用于快速、高通量分析中药成分。