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The effectiveness of leucocyte-poor platelet-rich plasma injections on symptomatic early osteoarthritis of the knee: the PEAK randomized controlled trial.
The Bone & Joint Journal ( IF 4.6 ) Pub Date : 2022-6-1 , DOI: 10.1302/0301-620x.104b6.bjj-2021-1109.r2
Emma Lewis 1 , Khalid Merghani 1 , Iain Robertson 2, 3 , Jonathon Mulford 1 , Ben Prentice 1 , Ronnie Mathew 1 , Peter Van Winden 1 , Kathryn Ogden 2, 3
Affiliation  

Platelet-rich plasma (PRP) intra-articular injections may provide a simple and minimally invasive treatment for early-stage knee osteoarthritis (OA). This has led to an increase in its adoption as a treatment for knee OA, although there is uncertainty about its efficacy and benefit. We hypothesized that patients with early-stage symptomatic knee OA who receive multiple PRP injections will have better clinical outcomes than those receiving single PRP or placebo injections.

中文翻译:

白细胞贫乏的富含血小板的血浆注射对有症状的膝关节早期骨关节炎的有效性:PEAK 随机对照试验。

富血小板血浆 (PRP) 关节内注射可为早期膝关节骨性关节炎 (OA) 提供简单且微创的治疗方法。这导致其作为膝关节 OA 治疗的采用增加,尽管其疗效和益处尚不确定。我们假设接受多次 PRP 注射的早期症状性膝关节 OA 患者将比接受单次 PRP 或安慰剂注射的患者具有更好的临床结果。
更新日期:2022-06-01
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