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Effect of locally applied simvastatin on clinical attachment level and alveolar bone in periodontal maintenance patients: A randomized clinical trial
Journal of Periodontology ( IF 4.3 ) Pub Date : 2022-05-27 , DOI: 10.1002/jper.21-0708
Amy C Killeen 1 , Lauren E Krell 1 , Mattie Bertels 1 , Mary M Christiansen 1 , Laura Anderson 1 , Robin L Hattervig 2 , Kaeli K Samson 3 , Dong Wang 4 , Richard A Reinhardt 1
Affiliation  

The purpose of this double-masked, randomized, controlled trial was to determine if the local application of simvastatin (SIM), combined with minimally invasive papilla reflection and root planing (PR/RP), is effective in improving clinical attachment level (CAL), probing depth (PD) reduction, and increasing interproximal bone height (IBH) in persistent 6–9 mm periodontal pockets in patients receiving periodontal maintenance therapy (PMT).

中文翻译:

局部应用辛伐他汀对牙周维护患者临床附着水平和牙槽骨的影响:一项随机临床试验

这项双盲、随机、对照试验的目的是确定局部应用辛伐他汀 (SIM) 并结合微创乳头反射和根面平整术 (PR/RP) 是否能有效改善临床附着水平 (CAL)在接受牙周维持治疗 (PMT) 的患者中,持久性 6-9 mm 牙周袋中的探诊深度 (PD) 减少和邻间骨高度 (IBH) 增加。
更新日期:2022-05-27
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