Reverberating throughout neuro-ophthalmology training programs is an informal proverb that the eye is a window into the brain. Almost every neurologic disease may have an ocular manifestation. Multiple sclerosis (MS) is no exception and for retinal imaging has been the prototype application of optical coherence tomography (OCT) in neurologic disease. While publications demonstrating the utility of OCT outcomes as biomarkers in MS have exponentially increased over 20 years,¹ the most critical results have emerged in the last few years, showing that OCT measures may have predictive value for disease course and may be sensitive to treatment effects.

在整个神经眼科培训计划中回荡是一句非正式的谚语，即眼睛是进入大脑的窗口。几乎每一种神经系统疾病都可能有眼部表现。多发性硬化症 (MS) 也不例外，视网膜成像一直是光学相干断层扫描 (OCT) 在神经系统疾病中的原型应用。虽然证明 OCT 结果作为 MS 生物标志物效用的出版物在 20 年内呈指数级增长，¹最关键的结果在过去几年出现，表明 OCT 测量可能对疾病过程具有预测价值，并且可能对治疗效果敏感.