当前位置: X-MOL 学术Eur. Respir. J. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Benefit of monoclonal antibodies in early treatment of COVID-19 after lung transplantation: a retrospective analysis in two centres
European Respiratory Journal ( IF 24.3 ) Pub Date : 2022-07-21 , DOI: 10.1183/13993003.00124-2022
Jens Gottlieb 1, 2 , Martin Kolditz 2, 3 , Nils Gade 4 , Tobias Welte 5, 6 , Nikolaus Kneidinger 6, 7
Affiliation  

Transplant recipients are at risk for poor outcomes from coronavirus disease 2019 (COVID-19) due to frequent medical comorbidities and presence of immunosuppression. Observational cohort studies suggest that patients after lung transplantation (LTx) with COVID-19 may have higher mortality in comparison to other solid organ transplant recipients. In a US retrospective analysis in the beginning of 2020, 78% of infected transplant patients were hospitalised and 19% died within 28 days [1]. Recently, both mortality and hospitalisation rate have declined in transplanted patients [2] and reduced mortality has been associated with vaccination [3].



中文翻译:

单克隆抗体在肺移植后 COVID-19 早期治疗中的益处:两个中心的回顾性分析

由于频繁的医学合并症和免疫抑制的存在,移植受者面临 2019 年冠状病毒病 (COVID-19) 的不良预后风险。观察性队列研究表明,与其他实体器官移植受者相比,肺移植 (LTx) 后 COVID-19 患者的死亡率可能更高。在 2020 年初的一项美国回顾性分析中,78% 的感染移植患者住院治疗,19% 的患者在 28 天内死亡 [1]。最近,移植患者的死亡率和住院率均有所下降 [2],而死亡率的降低与疫苗接种有关 [3]。

更新日期:2022-07-21
down
wechat
bug