Although significant advances have been made in the field to date, gender-based issues for women remain a neglected area in much of substance abuse research. In the current study we examined two gaps in the literature: the co-occurrence of compulsive sexual behavior disorder (CSBD) and risky sexual action tendencies among women with substance use disorders (SUDs), and their shared antecedents in the form of early life adversity and negative life events. The sample comprised 132 women of whom 62 had substance use disorder (drug and alcohol) and 70 were healthy controls. Each participant completed self-report measures of drug abuse and alcoholism, compulsive sexual behavior disorder and risky sexual action tendencies as well as early-life trauma and negative and positive life events. Results indicate that young women with substance use disorder have higher compulsive sexual behavior disorder symptoms and more prevalent risky sexual action tendencies than controls. Compulsive sexual behavior was also found to mediate the association between substance use and risky sexual action tendencies. In addition, all addictive behaviors were linked with emotional abuse at childhood but not with other types of abuse. Conversely, negative life events in adulthood were only linked with CSBD and not with substance use. The findings provide deeper insights into the comorbidity of addictive behaviors and an opportunity for developing more effective treatments for women who suffer from these addictions.

尽管迄今为止该领域取得了重大进展，但在许多药物滥用研究中，基于性别的女性问题仍然是一个被忽视的领域。在目前的研究中，我们检查了文献中的两个空白：患有物质使用障碍 (SUD) 的女性同时出现强迫性行为障碍 (CSBD) 和危险的性行为倾向，以及它们以早年逆境形式存在的共同前因和消极的生活事件。样本包括 132 名女性，其中 62 名患有物质使用障碍（药物和酒精），70 名是健康对照。每个参与者完成了关于药物滥用和酗酒、强迫性行为障碍和危险性行为倾向以及早期生活创伤和消极和积极生活事件的自我报告措施。结果表明，与对照组相比，患有物质使用障碍的年轻女性具有更高的强迫性行为障碍症状和更普遍的危险性行为倾向。还发现强迫性行为可以调节物质使用与危险性行为倾向之间的关联。此外，所有成瘾行为都与童年时期的情感虐待有关，但与其他类型的虐待无关。相反，成年期的负面生活事件仅与 CSBD 相关，与物质使用无关。这些发现为成瘾行为的合并症提供了更深入的见解，并为为患有这些成瘾的女性开发更有效的治疗方法提供了机会。还发现强迫性行为可以调节物质使用与危险性行为倾向之间的关联。此外，所有成瘾行为都与童年时期的情感虐待有关，但与其他类型的虐待无关。相反，成年期的负面生活事件仅与 CSBD 相关，与物质使用无关。这些发现为成瘾行为的合并症提供了更深入的见解，并为为患有这些成瘾的女性开发更有效的治疗方法提供了机会。还发现强迫性行为可以调节物质使用与危险性行为倾向之间的关联。此外，所有成瘾行为都与童年时期的情感虐待有关，但与其他类型的虐待无关。相反，成年期的负面生活事件仅与 CSBD 相关，与物质使用无关。这些发现为成瘾行为的合并症提供了更深入的见解，并为为患有这些成瘾的女性开发更有效的治疗方法提供了机会。