Abstract

Background

The increased use of illicit drugs continues to lead to the discovery of various unexpected pathologies.

Case presentation

This 7-month-old infant died suddenly at home. Pulmonary artery fibrinoid necrosis, diffuse fatty liver changes, and skin rash were the main histologic postmortem findings. Postmortem urine contained traces of methamphetamine. Methamphetamine was smoked by the parents.

Conclusions

Fibrinoid necrosis has been described with inhaling methamphetamine and can result in fibrinoid angiitis such as in this case. Although this did not result in pulmonary hemorrhage or could be directly related to death, it does suggest that pulmonary artery fibrinoid necrosis may develop with passive inhalation of methamphetamines.

中文翻译：

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甲基苯丙胺阳性婴儿的肺、肝和皮肤变化

摘要

背景

非法药物使用的增加继续导致发现各种意想不到的病症。

案例展示

这名7个月大的婴儿在家中突然死亡。肺动脉纤维蛋白样坏死、弥漫性脂肪肝改变和皮疹是主要的组织学尸检结果。死后尿液中含有微量甲基苯丙胺。甲基苯丙胺被父母吸食。

结论

纤维蛋白样坏死已被描述为吸入甲基苯丙胺，并可能导致纤维蛋白样血管炎，例如本例。虽然这并未导致肺出血或可能与死亡直接相关，但它确实表明肺动脉纤维蛋白样坏死可能会随着甲基苯丙胺的被动吸入而发展。