ABSTRACT

To describe and analyze the changes in anthropometric parameters in children with congenital Zika syndrome (CZS) from birth to four years of age. This prospective study evaluated 117 children diagnosed with CZS. Anthropometric indices evaluated annually were classified with respect to presence of microcephaly and adequacy of weight-for-age, length/height for-age and body mass index-for-age (BMI-for-age). At birth, 69.6% of the children had microcephaly, 90.2% had adequate weight and 72.1% had adequate length. The following year, an increase occurred in the proportion of children with microcephaly, with a reduction of those with adequate weight. In the second year, the proportion of children with microcephaly increased again, while those with adequate BMI decreased. In the third to fourth years of life, a reduction was found in the proportion of children with adequate height. Anthropometric indices are affected in children with CZS over the first four years of life and appear to be potentiated over time.

摘要

描述和分析先天性寨卡综合征 (CZS) 儿童从出生到四岁期间人体测量参数的变化。这项前瞻性研究评估了 117 名被诊断患有 CZS 的儿童。每年评估的人体测量指标根据小头畸形的存在和年龄别体重、年龄别身长/身高和年龄别体重指数（BMI-for-age）的充分性进行分类。出生时，69.6%的儿童有小头畸形，90.2%的体重合适，72.1%的身高合适。第二年，小头畸形儿童的比例有所增加，而体重正常的儿童比例有所下降。第二年，小头畸形儿童的比例再次上升，而BMI适中的儿童比例下降。在生命的第三到第四年，身高适中的儿童比例有所下降。人体测量指标在出生后的前四年内受到 CZS 儿童的影响，并且似乎随着时间的推移而增强。