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Performance of the Sofia SARS-CoV-2 Rapid Antigen Test in Symptomatic and Asymptomatic Pediatric Patients.
Journal of the Pediatric Infectious Diseases Society ( IF 3.2 ) Pub Date : 2022-09-29 , DOI: 10.1093/jpids/piac035
Megan Culler Freeman 1 , Tanner J Freeman 2 , Jennifer Iagnemma 3 , Jayne Rasmussen 4 , Kelly Heidenreich 3 , Alan Wells 2 , Alejandro Hoberman 5 , Stephanie L Mitchell 2
Affiliation  

The sensitivity and specificity of SARS-CoV-2 antigen tests have not been widely assessed in children. We evaluated children presenting to outpatient care with Quidel Sofia SARS-CoV-2 antigen test (Sofia-Ag-RDT) compared against Cepheid Xpert Xpress SARS-CoV-2/Flu/RSV reverse transcriptase-polymerase chain reaction test from November 2020 to April 2021. Sofia-Ag-RDT had the highest sensitivity in symptomatic (82%; 95% confidence interval, 68%-91%) children.

中文翻译:

Sofia SARS-CoV-2 快速抗原检测在有症状和无症状儿科患者中的表现。

SARS-CoV-2 抗原检测的敏感性和特异性尚未在儿童中得到广泛评估。我们对 2020 年 11 月至 4 月期间接受 Quidel Sofia SARS-CoV-2 抗原检测 (Sofia-Ag-RDT) 与 Cepheid Xpert Xpress SARS-CoV-2/Flu/RSV 逆转录酶-聚合酶链反应检测的儿童进行评估2021. Sofia-Ag-RDT 对有症状儿童的敏感性最高(82%;95% 置信区间,68%-91%)。
更新日期:2022-05-24
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