Poor vitamin D status is a global health problem; insufficiency underpins higher risk of cancer, neurocognitive decline and all-cause mortality. Most foods contain little vitamin D and plants are very poor sources. We have engineered the accumulation of provitamin D₃ in tomato by genome editing, modifying a duplicated section of phytosterol biosynthesis in Solanaceous plants, to provide a biofortified food with the added possibility of supplement production from waste material.

中文翻译：

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生物强化西红柿为补充维生素 D 提供了一条新途径

维生素 D 状况不佳是一个全球性的健康问题；不足会导致更高的癌症风险、神经认知能力下降和全因死亡率。大多数食物含有很少的维生素 D，而植物是非常贫乏的来源。_{我们通过基因组编辑设计了番茄中维生素原 D 3}的积累，修改了茄科植物中植物甾醇生物合成的复制部分，以提供一种生物强化食品，增加了从废料中生产补充剂的可能性。