AimThis study aimed to investigate the relationship between sarcopenia and change in bone mineral density (BMD) and functional outcome in hip arthroplasty patients. Methods: Among the 221 patients who had undergone hip arthroplasty, 147 patients were enrolled. All patients were divided into 2 groups according to presence of sarcopenia. Bone mineral density (BMD) at hospitalization and 1-year after surgery and Barthel index was measured at the time of before injury, hospitalization, 3 months and 1-year after surgery. Results: BMD at hospitalization showed .627 ± .082 (g/cm2) in Sarcopenia and .726 ± .059 (g/cm2) in Non-sarcopenia at femur (total) site (P < .001), .531 ± .085 (g/cm2) vs .629 ± .057 (g/cm2) at femur neck site (P=.002), .715 ± .084 (g/cm2) vs .807 ± .058 (g/cm2) at lumbar (L1-L4) site (P < .001). BMD at 1-year follow-up period, Sarcopenia showed .626 ± .082 (g/cm2) and Non-sarcopenia showed .725 ± .060 (g/cm2) at femur (total) site (P < .001), .530 ± .085 (g/cm2) vs .629 ± .058 (g/cm2) at femur neck site (P < .001), .715 ± .084 (g/cm2) vs .806 ± .058 (g/cm2) at lumbar (L1-L4) site (P < .001). Change of BMD showed −.01 ± .25% for Sarcopenia and −.15 ± .47% for Non-sarcopenia in femur (total) site (P=.089), −.08 ± .63% vs −.01 ± 1.01% in femur neck site (P = .058), .00 ± .09% vs −.12 ± .33% for each group in lumbar (L1-L4) site (P = .052). Barthel index score showed 79.94 ± 5.66 for Sarcopenia and 84.74 ± 5.36 for Non-sarcopenia at pre-injury status (P < .001), 33.89 ± 4.94 vs 33.87 ± 5.36 at the time of hospitalization (P = .977), 57.42 ± 7.19 vs 60.06 ± 5.39 at 3 months follow up (P = .015), 73.86 ± 5.94 vs 80.71 ± 4.81 for each group at 1-year follow up (P < .001). Conclusions: Our study found that the sarcopenia showed lower BMD than the non-sarcopenia, but there was no significant difference of BMD change in the follow-up period. In addition, the sarcopenia showed poor functional results at all points except at the time of hospitalization.

中文翻译：

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老年髋关节置换术患者肌肉减少症及其与骨矿物质密度和功能结果变化的关系

目的本研究旨在探讨髋关节置换术患者肌肉减少症与骨矿物质密度 (BMD) 变化和功能结果之间的关系。方法：在221例接受髋关节置换术的患者中，入组147例。根据有无肌肉减少症将所有患者分为2组。分别在伤前、住院、术后3个月、术后1年测量住院和术后1年的骨密度（BMD）和Barthel指数。结果：住院时的骨密度显示，股骨（总）部位的肌肉减少症为 0.627 ± .082 (g/cm2)，非肌肉减少症为 0.726 ± .059 (g/cm2)（P< .001), .531 ± .085 (g/cm2) vs .629 ± .057 (g/cm2) 在股骨颈部位 (P=.002), .715 ± .084 (g/cm2) vs .807 ± 0.058 (g/cm2) 在腰部 (L1-L4) 部位 ( P < .001)。1 年随访期间的 BMD，股骨（总）部位肌肉减少症显示 0.626 ± .082 (g/cm2)，非肌肉减少症显示 0.725 ± .060 (g/cm2) ( P < .001)， .530 ± .085 (g/cm2) vs .629 ± .058 (g/cm2) 在股骨颈部位 ( P < .001), .715 ± .084 (g/cm2) vs .806 ± .058 (g /cm2) 在腰椎 (L1-L4) 部位 ( P < .001)。股骨（总）部位的 BMD 变化显示肌肉减少症为 -.01 ± .25%，非肌肉减少症为 -.15 ± .47% (P=.089)，-.08 ± .63% 与 -.01 ±股骨颈部位 ( P = .058) 为 1.01%，腰椎 (L1-L4) 部位各组为 0.00 ± .09% 与 -.12 ± .33% ( P= .052)。Barthel 指数评分显示，在受伤前，肌肉减少症为 79.94 ± 5.66，非肌肉减少症为 84.74 ± 5.36 ( P < .001)，住院时为 33.89 ± 4.94 vs 33.87 ± 5.36 ( P = .977)，57.42 ± 7.19 vs 60.06 ± 5.39 在 3 个月的随访中（P = .015），73.86 ± 5.94 vs 80.71 ± 4.81 在 1 年的随访中（P < .001）。结论：我们的研究发现，肌少症患者的骨密度低于非肌少症患者，但随访期间骨密度变化无显着差异。此外，除了住院时，肌肉减少症在所有时间点的功能结果都很差。