Caspases are often considered the final checkpoint for a pathogen to save its replicative niche from collapsing after cell death signaling has been initiated in response to infection. Two recent works (Li et al., 2021; Peng et al., 2022) found that pathogens inhibit host cell death by inactivating multiple caspases with a novel posttranslational modification.

中文翻译：

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通过细菌病原体维护家庭完整性：为建设而中断

半胱天冬酶通常被认为是病原体的最终检查点，以在响应感染启动细胞死亡信号后挽救其复制生态位免于崩溃。最近的两项工作 (Li et al., 2021; Peng et al., 2022) 发现病原体通过一种新的翻译后修饰使多个半胱天冬酶失活来抑制宿主细胞死亡。