A formal [4 + 1] cycloaddition reaction of Baylis–Hillman adducts with sulfur ylides has been developed for the first time. This protocol features high functional group tolerance and provides facile access to biologically interesting α-alkenyl lactones with generally high yields. Meanwhile, the DFT calculation of the pathways has also been performed.

中文翻译：

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Baylis-Hillman 溴化物与硫叶立德的正式 [4 + 1] 环加成反应：容易获得 α-烯基内酯

首次开发了 Baylis-Hillman 加合物与硫叶立德的正式 [4 + 1] 环加成反应。该协议具有高官能团耐受性，可轻松获得具有生物学意义的 α-烯基内酯，且产量普遍较高。同时，还进行了路径的 DFT 计算。